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Article

[Diabetes in infants may be treated with sulfonylurea as a replacement for insulin].

Ugeskrift for laeger - 1 Jun 2009

Lauridsen Mette Høj, Boesgaard Trine Welløv, Pedersen Oluf Borbye, Hansen Torben, Hertz Birgitte

Abstract excerpt

A two-month-old Danish girl was admitted to the hospital in diabetic ketoacidosis and diagnosed with permanent neonatal diabetes mellitus (PNDM). She received continuous insulin treatment until she was genetically tested at the Steno Diabetes Centre. She carried a KCNJ11 Arg201His mutation, an activating mutation in the KCNJ11-gene which encodes the ATP-sensitive potassium subunit Kir6.2 in the beta cell which is...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19500515

Genes

KCNJ11

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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[Diabetes in infants may be treated with sulfonylurea as a replacement for insulin].PMID 19500515Read ↗

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Permanent neonatal diabetes by a new mutation in KCNJ11: unsuccessful switch to sulfonylurea.Semantic proximity Read ↗

[From gene to disease; neonatal diabetes mellitus and the KCNJ11 gene].Semantic proximity Read ↗

Sulfonylurea treatment outweighs insulin therapy in short-term metabolic control of patients with permanent neonatal diabetes mellitus due to activating mutations of the KCNJ11 (KIR6.2) geneSemantic proximity Read ↗

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