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Article

High-sensitive microarray substrates specifically designed to improve sensitivity for the identification of fetal paternally inherited sequences in maternal plasma.

Clinical chemistry and laboratory medicine - 1 Jan 2009

Bruno Francesca, Damin Francesco, Causarano Vincenza, Galbiati Silvia, Di Carlo Gabriele, Seia Manuela, Porcaro Luigi, Ferrari Maurizio, Chiari Marcella, Cremonesi Laura

Abstract excerpt

BACKGROUND: The identification of very low-levels of minority sequences has interesting clinical and diagnostic applications. Among these, non-invasive prenatal diagnosis of genetic diseases on fetal DNA circulating in maternal plasma is an emerging field of application. METHODS: A combined approach based on innovative microarray slides coated with a special copolymer was developed for the identification of three...

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Identifiers

PMID: 19496735
DOI: 10.1515/CCLM.2009.187

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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