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Article

Haematological & molecular profile of acute myelogenous leukaemia in India.

The Indian journal of medical research - 1 Mar 2009

Sazawal Sudha, Kumar Bijender, Hasan Syed Khizer, Dutta Pankhi, Kumar Rajat, Chaubey Rekha, Mir Rashid, Saxena Renu

Abstract excerpt

BACKGROUND & OBJECTIVE: Recurrent balanced translocations are generally recognized to be a major parameter for prognostication in acute myeloid leukaemia (AML). The chromosomal translocation t(15;17) results in PML/RARalpha fusion gene, t(8;21) results in AML1/ETO fusion gene and Inv 16 generates CBFbeta/MYH11 fusion gene. Patients with these mutations have a good prognosis unlike abnormalities in chromosome 5 or...

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Share to Core Binding Factor Alpha 2 Subunit
Share to fms-Like Tyrosine Kinase 3

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Duplication

Share to Leukemia, Myeloid, Acute

Share to Oncogene Proteins, Fusion

Share to RUNX1 Translocation Partner 1 Protein

Share to Translocation, Genetic

Source

Identifiers

PMID: 19491417

Genes

FLT3
PML
MYH11

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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