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Article

Alpha1-antitrypsin Pittsburgh in a family with bleeding tendency.

Haematologica - 1 Jun 2009

Hua Baolai, Fan Liankai, Liang Yan, Zhao Yongqiang, Tuddenham Edward G D

Abstract excerpt

We describe a 16-year-old girl and her 41-year-old father who both had a bleeding tendency, dramatic prolongation of all standard clotting assays, undetectable levels of plasma protein C activity, and low or borderline levels of factors X, XI and XII. Plasma and serum electrophoresis revealed a minor peak following the main alpha(1) globulin peak, of which the proportion was increased. Platelet aggregation by...

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Identifiers

PMID: 19483159
DOI: 10.3324/haematol.2008.004739
PMCID: PMC2688583

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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