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Article

Reciprocal interactions of obstructive sleep apnea and hypertension associated with ACE I/D polymorphism in males.

Sleep medicine - 1 Dec 2009

Koyama Renata G, Drager Luciano F, Lorenzi-Filho Geraldo, Cintra Fátima D, Pereira Alexandre C, Poyares Dalva, Krieger José Eduardo, Castro Rosa M R P S, Tufik Sérgio, de Mello Marco Túlio, Pedrazzoli Mario

Abstract excerpt

BACKGROUND: The angiotensin-converting enzyme (ACE) insertion/deletion (I/D) polymorphism gene contributes to the genesis of hypertension (HTN) and may help explain the relationship between obstructive sleep apnea (OSA) and HTN. However, ACE is a pleiotropic gene that has several influences, including skeletal muscle and control of ventilation. We therefore tested the hypothesis that ACE polymorphism influences...

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Source

Identifiers

PMID: 19482546
DOI: 10.1016/j.sleep.2008.12.012

Genes

ACE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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