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Article

A tyramine-gated chloride channel coordinates distinct motor programs of a Caenorhabditis elegans escape response.

Neuron - 28 May 2009

Pirri Jennifer K, McPherson Adam D, Donnelly Jamie L, Francis Michael M, Alkema Mark J

Abstract excerpt

A key feature of escape responses is the fast translation of sensory information into a coordinated motor output. In C. elegans, anterior touch initiates a backward escape response in which lateral head movements are suppressed. Here, we show that tyramine inhibits head movements and forward locomotion through the activation of a tyramine-gated chloride channel, LGC-55. lgc-55 mutant animals have defects in...

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Identifiers

PMID: 19477154
DOI: 10.1016/j.neuron.2009.04.013
PMCID: PMC2804440

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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