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Article

Nucleotide diversity of the Chlamydomonas reinhardtii plastid genome: addressing the mutational-hazard hypothesis.

BMC evolutionary biology - 27 May 2009

Smith David Roy, Lee Robert W

Abstract excerpt

BACKGROUND: The mutational-hazard hypothesis argues that the noncoding-DNA content of a genome is a consequence of the mutation rate (mu) and the effective number of genes per locus in the population (N(g)). The hypothesis predicts that genomes with a high N(g)mu will be more compact than those with a small N(g)mu. Approximations of N(g)mu can be gained by measuring the nucleotide diversity at silent sites...

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Source

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Identifiers

PMID: 19473533
DOI: 10.1186/1471-2148-9-120
PMCID: PMC2698885

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