Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Enhancement of methyl methanesulfonate-induced base excision repair in the presence of selenomethionine on p53-dependent pathway.

Journal of medicinal food - 1 Apr 2009

Jung Hwa Jin, Lee Ju Han, Seo Young R

Abstract excerpt

Selenomethionine (SeMet) has been identified as a chemopreventive antioxidant to activate p53-mediated nucleotide excision repair. In this study, we examined whether p53-mediated base excision repair (BER) might be induced by SeMet. When methyl methanesulfonate, a BER-inducing agent, was treated in the cells, DNA damage was rapidly decreased in the presence of SeMet. In addition, our data showed that the removal...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antioxidants
Share to Cell Cycle Proteins
Share to DNA Damage

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA Repair

Share to Methyl Methanesulfonate

Share to Nuclear Proteins

Share to RNA, Small Interfering

Share to Tumor Suppressor Protein p53

Source

Identifiers

PMID: 19459735
DOI: 10.1089/jmf.2007.0709

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 10 closest

Enhancement of methyl methanesulfonate-induced base excision repair in the presence of selenomethionine on p53-dependent pathway.PMID 19459735Read ↗

Protective effects of selenomethionine against ionizing radiation under the modulation of p53 tumor suppressor.Semantic proximity Read ↗

Chemoprotective action of L-(+)-selenomethionine on the modulation of genes involved in oxidative stress and in the UPR pathwaySemantic proximity Read ↗

SELENOT–Knockdown Leads to Reducing the Expression of Key Enzymes of ERAD–System in Cancer Cells Under ER–StressSemantic proximity Read ↗

Selenomethionine induction of DNA repair response in human fibroblastsSemantic proximity Read ↗

Selenocystine induces reactive oxygen species–mediated apoptosis in human cancer cellsSemantic proximity Read ↗

Selenoproteins reduce susceptibility to DMBA-induced mammary carcinogenesis.Semantic proximity Read ↗

Contrasting roles of dietary selenium and selenoproteins in chemically induced hepatocarcinogenesis.Semantic proximity Read ↗

Investigations on the role of base excision repair and non-homologous end-joining pathways in sodium selenite-induced toxicity and mutagenicity in Saccharomyces cerevisiae.Semantic proximity Read ↗

Differential involvement of reactive oxygen species in apoptosis induced by two classes of selenium compounds in human prostate cancer cellsSemantic proximity Read ↗

Expression of securin promotes colorectal cancer cell death via a p53-independent pathway after radiation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.