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Article

Fetal Alcohol Spectrum Disorders: The Epigenetic Perspective1

21 May 2009

Abstract excerpt

Ethanol is a classic teratogen capable of inducing a wide range of developmental abnormalities. Studies in animal models suggest that differences in timing and dosage underlie this variability, with three particularly important developmental periods: preconception, preimplantation, and gastrulation. These periods of teratogenesis correlate with peak periods of epigenetic reprogramming which, together with the...

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PMID: 19458312
DOI: 10.1095/biolreprod.108.074690

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