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Article

Increased intrasubject variability in response time in youths with bipolar disorder and at-risk family members.

Journal of the American Academy of Child and Adolescent Psychiatry - 1 Jun 2009

Brotman Melissa A, Rooney Melissa H, Skup Martha, Pine Daniel S, Leibenluft Ellen

Abstract excerpt

OBJECTIVE: Deficits in sustained attention may represent an endophenotype for bipolar disorder (BD). One heritable measure of sustained attention is intrasubject variability in response time (ISV-RT). We tested the hypothesis that, compared with controls, both youths with BD and those at familial risk for the disorder would have increased ISV-RT. METHOD: Subjects were 28 patients with BD, 26 unaffected youths...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19454918
DOI: 10.1097/CHI.0b013e3181a27527
PMCID: PMC2787201

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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