Article
Sickle cell disease as a cause of osteonecrosis of the femoral head.
The New England journal of medicine - 21 Nov 1991
Milner P F, Kraus A P, Sebes J I, Sleeper L A, Dukes K A, Embury S H, Bellevue R, Koshy M, Moohr J W, Smith J
Abstract excerpt
BACKGROUND AND METHODS: Osteonecrosis of the femoral head is an important complication of sickle cell disease. We studied 2590 patients who were over 5 years of age at entry and followed them for an average of 5.6 years. Patients were examined twice a year, and radiographs of the hips were taken at least twice: at study entry and approximately three years later. RESULTS: At study entry, 9.8 percent of patients...
Topics
- Adolescent
- Adult
- Anemia, Sickle Cell
- Child
- Child, Preschool
- Femur Head Necrosis
- Genotype
- Hemoglobin, Sickle
- Humans
- Middle Aged
- Thalassemia