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Limited Transcriptional Responses of Rickettsia rickettsii Exposed to Environmental Stimuli

18 May 2009

Abstract excerpt

Rickettsiae are strict obligate intracellular pathogens that alternate between arthropod and mammalian hosts in a zoonotic cycle. Typically, pathogenic bacteria that cycle between environmental sources and mammalian hosts adapt to the respective environments by coordinately regulating gene expression such that genes essential for survival and virulence are expressed only upon infection of mammals. Temperature is...

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PMID: 19440298
DOI: 10.1371/journal.pone.0005612

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