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Article

Impact of x chromosome genes in explaining the excess risk of cancer in males.

American journal of epidemiology - 1 Jul 2009

Biggar Robert J, Bergen Andrew W, Poulsen Gry N

Abstract excerpt

The authors examined cancer incidence sex ratios in Denmark for 1943-2003 by age group. At nongenital/nonbreast sites, incidences were consistently higher in males. While environmental factors dominate cancer risk, the authors hypothesized that the higher risk in males might be explained by unspecified X chromosome genes' protecting female cells from genotoxic damage. If so, cancer susceptibility would be passed...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 19433615
DOI: 10.1093/aje/kwp083

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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