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Comparison of Viral Shedding Following Vaccination With Inactivated and Live Newcastle Disease Vaccines Formulated With Wild-Type and Recombinant Viruses

1 Mar 2009

Abstract excerpt

Virulent Newcastle disease virus isolates from the 1971 and 2002 U.S. outbreaks are of the same serotype but a different genotype than current vaccine strains. Prior experiments with inactivated vaccines in chickens show significantly less virus shed in birds vaccinated with a homologous vaccine (same genotype as challenge) compared to chickens vaccinated with genotypically heterologous vaccines. Subsequent...

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PMID: 19432002
DOI: 10.1637/8407-071208-reg.1

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