Article
The interplay of two single nucleotide polymorphisms in the CACNA1A gene may contribute to migraine susceptibility.
Neuroscience letters - 27 Mar 2009
D'Onofrio Mara, Ambrosini Anna, Di Mambro Alessandra, Arisi Ivan, Santorelli Filippo M, Grieco Gaetano S, Nicoletti Ferdinando, Nappi Giuseppe, Pierelli Francesco, Schoenen Jean, Buzzi Maria Gabriella
Abstract excerpt
Migraine is a common disorder with a significant genetic component. Mutations in the CACNA1A gene are found in hemiplegic migraine (HM). Basilar-type (BM), another subtype of migraine with aura, differs from HM only by the absence of motor deficits. BM and HM may thus share common genetic feature...
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