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Article

Network analysis of human glaucomatous optic nerve head astrocytes

9 May 2009

Abstract excerpt

BACKGROUND: Astrocyte activation is a characteristic response to injury in the central nervous system, and can be either neurotoxic or neuroprotective, while the regulation of both roles remains elusive. METHODS: To decipher the regulatory elements controlling astrocyte-mediated neurotoxicity in glaucoma, we conducted a systems-level functional analysis of gene expression, proteomic and genetic data associated...

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PMID: 19426536
DOI: 10.1186/1755-8794-2-24

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