Article
Characterisation of forward stutter in the AmpFlSTR SGM Plus PCR.
Science & justice : journal of the Forensic Science Society - 1 Mar 2009
Gibb Andrew J, Huell Andrea-Louise, Simmons Mark C, Brown Rosalind M
Abstract excerpt
PCR amplification of tetrameric short tandem repeats (STRs) can lead to Taq enzyme slippage and artefact products typically one repeat unit less in size than the parent STR. These back stutter or n-4 amplification products are low-level relative to the amplification of the parent STR but are widely seen in the forensic community where tetrameric STRs are employed in the generation of DNA profiles. To aid the...
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