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Article

EGFR inhibition using gefitinib is not active in neuroblastoma cell lines.

Anticancer research - 1 Apr 2009

Rössler Jochen, Odenthal Eva, Geoerger Birgit, Gerstenmeyer Aurore, Lagodny Jeanette, Niemeyer Charlotte Marie, Vassal Gilles

Abstract excerpt

BACKGROUND: Inhibition of the epidermal growth factor receptor (EGFR), using a tyrosine kinase inhibitor such as gefitinib, was suggested to be a new treatment approach for neuroblastoma. MATERIAL AND METHODS: EGFR expression and gene mutation were studied by reversetranscriptase-polxmerase chain reacting, fluorescence-activated cell sorting and gene sequencing in six neuroblastoma cell lines. In vitro...

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Source

Identifiers

PMID: 19414383

Genes

EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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