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Article

Reverse translational strategies for developing animal models of bipolar disorder.

Disease models & mechanisms - 1 Jan 2000

Malkesman Oz, Austin Daniel R, Chen Guang, Manji Husseini K

Abstract excerpt

Bipolar disorder (BD) affects a significant portion of the population of the world, yet there has been limited success in developing novel treatments for the disorder. One of the major reasons for this dearth is the absence of suitable animal models for BD. Traditionally, animal models of human phenomena have been evaluated based on similarity to the human syndrome, response to appropriately corresponding...

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Identifiers

PMID: 19407332
DOI: 10.1242/dmm.001628
PMCID: PMC2675806

Genes

POLG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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