Article
Impact of hepatitis B virus genotypes and surface antigen variants on the performance of HBV real time PCR quantification.
Journal of virological methods - 1 Aug 2009
Thibault Vincent, Laperche Syria, Akhavan Sepideh, Servant-Delmas Annabelle, Belkhiri Dalila, Roque-Afonso Anne-Marie
Abstract excerpt
Quantitative PCR assays used to monitor hepatitis B virus (HBV) load differ in their ability to detect different HBV variants. This study evaluated the performance of the Abbott RT PCR assay for quantitating DNA from different HBV genotypes and from HBV variants bearing HBsAg gene mutations. The study was performed on a randomly-selected sample with a viral load >6logIU/mL for each genotype and on 25 HBsAg...
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