Article
Genetic variations in a well conserved 5'-untranslated region of hepatitis C virus genome isolated in Pakistan.
Journal of virological methods - 1 Sept 2009
Yasmeen Anila, Siddiqui Anwar Ali, Hamid Saeed, Sultana Taranum, Jafri Wasim, Persson Mats A A
Abstract excerpt
The diversity and extent of sequence variations between hepatitis C virus (HCV) isolates from Pakistan were studied and the probable effects of these variations were assessed on secondary viral structures. Sequencing and phylogenetic analysis was performed on 33 samples, of which 25 were typed as genotype 3 by RFLP (restriction fragment length polymorphism) and 8 remained unresolved. Rooted neighbour-joining (NJ)...
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