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Article

The impact of crown–rump length measurement error on combined Down syndrome screening: a simulation study

28 Apr 2009

Abstract excerpt

OBJECTIVE: To evaluate the impact of a 5-mm error in the measurement of crown-rump length (CRL) in a woman undergoing ultrasound and biochemistry sequential combined screening for Down syndrome. METHODS: Based on existing risk calculation algorithms, we simulated the case of a 35-year-old-woman undergoing combined screening based on nuchal translucency (NT) measurement and early second-trimester maternal serum...

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PMID: 19402123
DOI: 10.1002/uog.6371

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