Article
Macrophages and adipocytes in human obesity: adipose tissue gene expression and insulin sensitivity during calorie restriction and weight stabilization.
Diabetes - 1 Jul 2009
Capel Frédéric, Klimcáková Eva, Viguerie Nathalie, Roussel Balbine, Vítková Michaela, Kováciková Michaela, Polák Jan, Kovácová Zuzana, Galitzky Jean, Maoret Jean-José, Hanácek Jirí, Pers Tune H, Bouloumié Anne, Stich Vladimir, Langin Dominique
Abstract excerpt
OBJECTIVE: We investigated the regulation of adipose tissue gene expression during different phases of a dietary weight loss program and its relation with insulin sensitivity. RESEARCH DESIGN AND METHODS: Twenty-two obese women followed a dietary intervention program composed of an energy restriction phase with a 4-week very-low-calorie diet and a weight stabilization period composed of a 2-month low-calorie diet...
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