Article
An outbreak of postoperative gram-negative bacterial endophthalmitis associated with contaminated trypan blue ophthalmic solution.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America - 1 Jun 2009
Sunenshine Rebecca, Schultz Maureen, Lawrence Mary G, Shin Soo, Jensen Bette, Zubairi Sabiha, Labriola Ann M, Shams Alicia, Noble-Wang Judith, Arduino Matthew J, Gordin Fred, Srinivasan Arjun
Abstract excerpt
We report 6 cases of postsurgical endophthalmitis due to gram-negative bacteria associated with contaminated trypan blue dye from a compounding pharmacy. Unopened trypan blue syringes yielded Pseudomonas aeruginosa and Burkholderia cepacia complex on culture, with pulsed-field gel electrophoresis patterns indistinguishable from patient isolates. Contamination of compounded medications should be considered when...
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