Analysis of HMB-45 immunoreactivity in common and cellular blue nevi.

Abstract excerpt

HMB-45 is generally thought of as a melanoma specific antibody; however, there are certain exceptions. It is known that most dermal nevi show no reactivity; however, the dermal nevus component within dysplastic nevi and certain Spitz nevi show positive reactivity. In order to further examine this observation, we undertook a study to examine blue nevi, both common and cellular, for the expression of HMB-45. Cases...

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