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Microbe-induced epigenetic alterations in host cells: The coming era of patho-epigenetics of microbial infections

1 Mar 2009

Abstract excerpt

It is well documented that the double-stranded DNA (dsDNA) genomes of certain viruses and the proviral genomes of retroviruses are regularly targeted by epigenetic regulatory mechanisms (DNA methylation, histone modifications, binding of regulatory proteins) in infected cells. In parallel, proteins encoded by viral genomes may affect the activity of a set of cellular promoters by interacting with the very same...

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PMID: 19388554
DOI: 10.1556/amicr.56.2009.1.1

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