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Mechanisms in Neisseria meningitidis for resistance against complement-mediated killing

1 Dec 2008

Abstract excerpt

Bacterial meningitis and septicaemia is a global health problem often caused by Neisseria meningitidis. The complement system is the most important aspect of host defence against this pathogen, and the critical interaction between the two is influenced by genetic polymorphisms on both the bacterial and the host side; variations of the meningococcus may lead to increased survival in human sera, whereas humans with...

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Identifiers

PMID: 19388162
DOI: 10.1016/j.vaccine.2008.11.059

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