Pediatric Helicobacter pylori isolates display distinct gene coding capacities and virulence gene marker profiles.

doi:10.1128/JCM.00273-09

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Article

Pediatric Helicobacter pylori isolates display distinct gene coding capacities and virulence gene marker profiles.

Journal of clinical microbiology - 1 Jun 2009

Talarico Sarah, Gold Benjamin D, Fero Jutta, Thompson Dexter T, Guarner Jeannette, Czinn Steven, Salama Nina R

Abstract excerpt

Helicobacter pylori strains display remarkable genetic diversity, and the presence of strains bearing the toxigenic vacA s1 allele, a complete cag pathogenicity island (PAI), cagA alleles containing multiple EPIYA phosphorylation sites, and expressing the BabA adhesin correlates with development of gastroduodenal disease in adults. To better understand the genetic variability present among pediatric strains and...

Topics

Adolescent
Bacterial Proteins
Bacterial Typing Techniques
Child
Child, Preschool
Comparative Genomic Hybridization
DNA Fingerprinting
Female
Genotype
Helicobacter Infections

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Helicobacter pylori

Humans

Male

North America

Random Amplified Polymorphic DNA Technique

Virulence Factors

Young Adult

Source

Open in PubMed Open full text

Identifiers

PMID: 19386830
DOI: 10.1128/JCM.00273-09
PMCID: PMC2691067

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-19386830-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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