Article
Pediatric Helicobacter pylori isolates display distinct gene coding capacities and virulence gene marker profiles.
Journal of clinical microbiology - 1 Jun 2009
Talarico Sarah, Gold Benjamin D, Fero Jutta, Thompson Dexter T, Guarner Jeannette, Czinn Steven, Salama Nina R
Abstract excerpt
Helicobacter pylori strains display remarkable genetic diversity, and the presence of strains bearing the toxigenic vacA s1 allele, a complete cag pathogenicity island (PAI), cagA alleles containing multiple EPIYA phosphorylation sites, and expressing the BabA adhesin correlates with development of gastroduodenal disease in adults. To better understand the genetic variability present among pediatric strains and...
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