Article
Analysis of the vacA, cagA, cagE, iceA, and babA2 genes in Helicobacter pylori from sixty-one pediatric patients from the Midwestern United States.
Diagnostic microbiology and infectious disease - 1 Jun 2003
Podzorski Raymond P, Podzorski Diane S, Wuerth Ann, Tolia Vasundhara
Abstract excerpt
This study was designed to characterize H. pylori from pediatric gastric biopsy specimens in terms of several genes (vacA, cagA, cagE, iceA1, iceA2, and babA2) proposed to be involved in the pathogenesis of this organism. Many of these genes have been studied in adult H. pylori isolates, however, these genes have not been well characterized in H. pylori from children. Using PCR we observed that 44% of the H....
Topics
- Adhesins, Bacterial
- Antigens, Bacterial
- Bacterial Outer Membrane Proteins
- Bacterial Proteins
- Base Sequence
- Biopsy, Needle
- Carrier Proteins
- Child
- Child, Preschool
- Cohort Studies