Article
Absence of genotypic drug resistance and presence of several naturally occurring polymorphisms of human immunodeficiency virus-1 CRF06_cpx in treatment-naive patients in Estonia.
Journal of medical virology - 1 Jun 2009
Avi Radko, Huik Kristi, Sadam Maarja, Karki Tonis, Krispin Tonu, Ainsalu Külliki, Paap Piret, Schmidt Jelena, Nikitina Natalia, Lutsar Irja
Abstract excerpt
All non-B HIV-1 subtypes and circulating recombinant forms (CRFs) are characterized by several polymorphisms in protease (PR) region. In addition, in recent years the increasing use of antiretroviral treatment (ART) has rapidly raised the spread of transmitted drug resistance. We aimed to determine the presence of naturally occurring polymorphisms and transmitted drug resistance mutations (DRMs) in ART naïve...
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