Article
Role of a cell surface-associated protein in adherence and dental caries.
Infection and immunity - 1 Dec 1991
Bowen W H, Schilling K, Giertsen E, Pearson S, Lee S F, Bleiweis A, Beeman D
Abstract excerpt
Insertional inactivation of the Streptococcus mutans spaP gene was used to construct an isogenic mutant (834) of strain NG8 (serotype c) which lacked the major cell surface-associated protein referred to as P1 (15). Results of several studies suggest that P1 is involved in the adherence of S. mutans to saliva-coated apatite surfaces. With an in vitro model system of hydroxyapatite (HA) beads coated with parotid...
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