Article
Effect of filamentation and mode of growth on antifungal susceptibility of Candida albicans.
International journal of antimicrobial agents - 1 Oct 2009
Watamoto T, Samaranayake L P, Jayatilake J A M S, Egusa H, Yatani H, Seneviratne C J
Abstract excerpt
Biofilm formation involving profuse hyphal growth is a major characteristic of Candida spp. and confers higher antifungal resistance than its planktonic mode of growth. We investigated the antifungal susceptibility of Candida albicans and its hyphal mutants (Delta efg1/efg1, Delta cph1/cph1 and DeltaDelta cph1/cph1 efg1/efg1) to commonly used antifungals during planktonic, adhesion and biofilm modes of growth....
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