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Article

Biofilms formed by Candida albicans bloodstream isolates display phenotypic and transcriptional heterogeneity that are associated with resistance and pathogenicity.

BMC microbiology - 5 Jul 2014

Sherry Leighann, Rajendran Ranjith, Lappin David F, Borghi Elisa, Perdoni Federica, Falleni Monica, Tosi Delfina, Smith Karen, Williams Craig, Jones Brian, Nile Chris J, Ramage Gordon

Abstract excerpt

BACKGROUND: Candida albicans infections have become increasingly recognised as being biofilm related. Recent studies have shown that there is a relationship between biofilm formation and poor clinical outcomes in patients infected with biofilm proficient strains. Here we have investigated a panel of clinical isolates in an attempt to evaluate their phenotypic and transcriptional properties in an attempt to...

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Identifiers

PMID: 24996549
DOI: 10.1186/1471-2180-14-182
PMCID: PMC4105547

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Source receipt: pubmed, retrieved 7 Sept 2026.

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