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Article

Prophylactic plasma exchange in CD46-associated atypical haemolytic uremic syndrome.

Pediatric nephrology (Berlin, Germany) - 1 Sept 2009

Davin Jean-Claude, Buter Nynke, Groothoff Jaap, van Wijk Joanna, Bouts Antonia, Strain Lisa, Goodship Tim

Abstract excerpt

Patients with atypical haemolytic uremic syndrome (aHUS) with a mutation in the gene encoding membrane cofactor protein (CD46) are known to have a better prognosis than those with mutations in factor H (CFH) or factor I (CFI), but a small number of the former still proceed to end-stage renal failure. Plasma therapy (PE) is the recommended approach to treat both acute episodes and prevent recurrences in aHUS, but...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19373492
DOI: 10.1007/s00467-009-1188-8
PMCID: PMC2719744

Genes

CFH
CFI

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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