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Article

Different clinical phenotypes in monozygotic CADASIL twins with a novel NOTCH3 mutation.

Stroke - 1 Jun 2009

Mykkänen Kati, Junna Maija, Amberla Kaarina, Bronge Lena, Kääriäinen Helena, Pöyhönen Minna, Kalimo Hannu, Viitanen Matti

Abstract excerpt

BACKGROUND AND PURPOSE: CADASIL is a hereditary arteriopathy causing recurrent strokes and cognitive decline. Because monozygotic twins have identical genetic background, differences in their environment and lifestyle could reveal factors that may influence CADASIL patients' clinical course, which is highly variable even within the same family. METHODS: We describe differences in clinical and imaging findings in...

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Source

Identifiers

PMID: 19372454
DOI: 10.1161/STROKEAHA.108.528661

Genes

NOTCH3

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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