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Article

Endothelin system polymorphisms in tilt test-induced vasovagal syncope.

Clinical autonomic research : official journal of the Clinical Autonomic Research Society - 1 Dec 2009

Sorrentino Sandro, Forleo Cinzia, Iacoviello Massimo, Guida Pietro, D'Andria Valentina, Favale Stefano

Abstract excerpt

INTRODUCTION: Genetics may be involved in the pathophysiology of vasovagal syncope. The 3A/4A polymorphism of the EDN1 gene affects the expression of endothelin-1, and the H323H T/C polymorphism of the EDNRA gene encoding for the endothelin type A receptor has been associated with cardiovascular pathologies. As the endothelin system participates in the regulation of cardiovascular homeostasis, the aim of this...

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Identifiers

PMID: 19367425
DOI: 10.1007/s10286-009-0008-3

Genes

EDN1
EDNRA

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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