Article
Mutation in CNR1 gene and VEGF expression in esophageal cancer.
Tumori - 1 Jan 2000
Bedoya Fernando, Meneu Juan C, Macías Maria Isabel, Moreno Almudena, Enríquez-De-Salamanca Rafael, Gonzalez Enrique Moreno, Vegh Irene
Abstract excerpt
AIMS AND BACKGROUND: Cannabinoid receptors have an impact on gastrointestinal function, but it remains unknown whether mutations may affect tumor susceptibility in patients with esophageal carcinoma. The aim of this study was to determine mutation in the cannabinoid receptor-1 (CNR1) gene and its relation to vascular endothelial growth factor (VEGF) expression as an angiogenic and poor prognostic factor. METHODS:...
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