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Elimination of by-product formation during production of 1,3-propanediol in Klebsiella pneumoniae by inactivation of glycerol oxidative pathway.

Applied microbiology and biotechnology - 1 Sept 2009

Seo Mi-Young, Seo Jeong-Woo, Heo Sun-Yeon, Baek Jin-Oh, Rairakhwada Dina, Oh Baek-Rock, Seo Pil-Soo, Choi Min Ho, Kim Chul Ho

Abstract excerpt

The microbial production of 1,3-propanediol (1,3-PD) by Klebsiella pneumoniae involves the formation of various by-products, which are synthesized through the oxidative pathway. To eliminate the by-products synthesis, the oxidative branch of glycerol metabolism was inactivated by constructing two mutant strains. In one of the mutant strains, the structural genes encoding glycerol dehydrogenase and...

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Identifiers

PMID: 19352645
DOI: 10.1007/s00253-009-1980-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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