MONITORING HUMAN RADIATION EXPOSURE BY GENE EXPRESSION PROFILING: POSSIBILITIES AND PITFALLS

Abstract excerpt

Advances in high throughput analysis of mRNA expression have made it possible to establish gene expression profiles for different cells, tissues, diseases and exposure states. For instance, recent studies have demonstrated the utility of such an approach to classify sub-types of cancers with more detail than was previously possible. In addition, gene expression studies of ionizing radiation exposure both in vitro...

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