Article
Frequency of mitochondrial defects in patients with chronic intestinal pseudo-obstruction.
Gastroenterology - 1 Jul 2009
Amiot Aurélien, Tchikviladzé Maya, Joly Francisca, Slama Abdelhamid, Hatem Dominique Cazals, Jardel Claude, Messing Bernard, Lombès Anne
Abstract excerpt
BACKGROUND & AIMS: Chronic intestinal pseudo-obstruction (CIPO) is a rare disorder caused by intestinal dysmotility and characterized by chronic symptoms suggesting bowel obstruction in the absence of fixed, occluding lesions. CIPO has been associated with primary defects of the mitochondrial oxidative phosphorylation pathway, although the frequency of mitochondrial disorders in patients with CIPO is unknown....
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