Article
Use-dependent plasticity in clock neurons regulates sleep need in Drosophila.
Science (New York, N.Y.) - 3 Apr 2009
Donlea Jeffrey M, Ramanan Narendrakumar, Shaw Paul J
Abstract excerpt
Sleep is important for memory consolidation and is responsive to waking experience. Clock circuitry is uniquely positioned to coordinate interactions between processes underlying memory and sleep need. Flies increase sleep both after exposure to an enriched social environment and after protocols that induce long-term memory. We found that flies mutant for rutabaga, period, and blistered were deficient for...
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