Article
Three‐dimensional visualization of testis cord morphogenesis, a novel tubulogenic mechanism in development
30 Mar 2009
Abstract excerpt
Testis cords are specialized tubes essential for generation and export of sperm, yet the mechanisms directing their formation, and the regulation of their position, size, shape, and number remain unclear. Here, we use a novel fluorescence-based three-dimensional modeling approach to show that cords initially form as a network of irregular cell clusters that are subsequently remodeled to form regular parallel...
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