Article
Wolframin gene H611R polymorphism: no direct association with suicidal behavior but possible link to mood disorders.
Progress in neuro-psychopharmacology & biological psychiatry - 15 Jun 2009
Zalsman Gil, Mann Mark J, Huang Yung-Yu, Oquendo Maria A, Brent David A, Burke Ainsley K, Ellis Steven P, Mann J John
Abstract excerpt
Wolframin gene polymorphisms, including the H611R polymorphism, are reportedly associated with mood disorders and psychiatric hospitalization, but there is disagreement about the association of this specific variant with suicidality and impulsive traits. This study tested the association of the H611R polymorphism with mood disorders, suicidal behavior, and aggressive-impulsive traits. Two hundred and one subjects...
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