Article
Immunomodulatory therapy with thymopentin and indomethacin. Successful restoration of interleukin-2 synthesis in patients undergoing major surgery.
Annals of surgery - 1 Sept 1991
Faist E, Markewitz A, Fuchs D, Lang S, Zarius S, Schildberg F W, Wachter H, Reichart B
Abstract excerpt
Prostaglandin E2 (PGE2)-mediated monocyte (M phi) suppressor activity and inadequate T-helper cell function represent the mechanistic keystones of trauma-induced impairment of cell-mediated immunity (CMI). In a prospective randomized trial, the immunorestorative potential of a combined therapy wi...
Topics
- Adjuvants, Immunologic
- Aged
- Antigens, CD
- Biopterins
- Cardiac Surgical Procedures
- Cell Division
- Drug Therapy, Combination
- Female
- Humans
- Hypersensitivity, Delayed
- Immunity, Cellular
- Indomethacin
- Interferon-gamma
- Interleukin-2