Effects of a preoperative therapy with interleukin-2 on surgery-induced lymphocytopenia in cancer patients.

doi:10.1159/000227041

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Article

Effects of a preoperative therapy with interleukin-2 on surgery-induced lymphocytopenia in cancer patients.

Oncology - 1 Jan 1992

Brivio F, Lissoni P, Tisi E, Erba L, Barni S, Tancini G, Rescaldani R, Alderi G, Nociti V

Abstract excerpt

It is known that major surgery may determine immunosuppression. This side effect might have a prognostic significance particularly in cancer patients, in whom the decrease in host defenses during the postoperative period could promote the proliferation of possible micrometastases. Since antitumor immune response is an IL-2-dependent phenomenon, a study was started to evaluate the effects of a preoperative...

Topics

Adult
Aged
Colorectal Neoplasms
Female
Genetic Variation
Humans
Immune Tolerance
Immunity, Cellular
Interleukin-2
Killer Cells, Natural
Leukocyte Count

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Lymphocytes

Lymphopenia

Male

Middle Aged

Postoperative Complications

Preoperative Care

Receptors, Interleukin-2

Source

Open in PubMed

Identifiers

PMID: 1495748
DOI: 10.1159/000227041

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1495748-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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