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Article

Genetic diversity of the malaria vaccine candidate Plasmodium falciparum merozoite surface protein-3 in a hypoendemic transmission environment.

The American journal of tropical medicine and hygiene - 1 Mar 2009

Jordan Stephen J, Branch OraLee H, Castro Juan Carlos, Castro Jean Carlos, Oster Robert A, Rayner Julian C

Abstract excerpt

The N-terminal domain of Plasmodium falciparum merozoite surface protein-3 (PfMSP3) has been excluded from malaria vaccine development largely because of genetic diversity concerns. However, no study to date has followed N-terminal diversity over time. This study describes PfMSP3 variation in a hypoendemic longitudinal cohort in the Peruvian Amazon over the 2003-2006 transmission seasons. Polymerase chain...

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Share to Antigens, Protozoan
Share to Chromatography, High Pressure Liquid

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Malaria, Falciparum

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Source

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Identifiers

PMID: 19270302
PMCID: PMC2723947

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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