[Various genetic models in Crohn disease].

Abstract excerpt

Crohn's disease has a genetic predisposition. In the light of epidemiological data, especially the type of familial clustering, simple modes of inheritance can be excluded. At the first glance, our results implied a polygenic multifactorial basis. Further processing of our data by the "mixed model" of Morton revealed a higher probability for a recessive gene with low penetrance. However, the differences in fit...

Topics

• Adolescent
• Adult
• Crohn Disease
• Female
• Gene Frequency
• Genes, Dominant
• Genetic Markers
• Genotype
• Humans
• Male
• Models, Genetic
• Risk Factors