Article
Serum ferritin is a clinical biomarker in Japanese patients with nonalcoholic steatohepatitis (NASH) independent of HFE gene mutation.
Digestive diseases and sciences - 1 Mar 2010
Yoneda Masato, Nozaki Yuichi, Endo Hiroki, Mawatari Hironori, Iida Hiroshi, Fujita Koji, Yoneda Kyoko, Takahashi Hirokazu, Kirikoshi Hiroyuki, Inamori Masahiko, Kobayashi Noritoshi, Kubota Kensuke, Saito Satoru, Maeyama Shiro, Hotta Kikuko, Nakajima Atsushi
Abstract excerpt
Nonalcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver injury. The spectrum of NAFLD is broad, extending from simple steatosis through nonalcoholic steatohepatitis (NASH). Iron is regarded as a putative element that interacts with oxygen radicals, and high rates of hyperferritinemia and increased hepatic iron stores have been demonstrated in NASH. We investigated serum ferritin...
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