Article
Typing SNP based on the near-infrared spectroscopy and artificial neural network.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy - 1 Jul 2009
Ren Li, Wang Wei-Peng, Gao Yu-Zhen, Yu Xiao-Wei, Xie Hong-Ping
Abstract excerpt
Based on the near-infrared spectra (NIRS) of the measured samples as the discriminant variables of their genotypes, the genotype discriminant model of SNP has been established by using back-propagation artificial neural network (BP-ANN). Taking a SNP (857G>A) of N-acetyltransferase 2 (NAT2) as an example, DNA fragments containing the SNP site were amplified by the PCR method based on a pair of primers to obtain...
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