Identification of glycoprotein receptors within the human salivary proteome for the lectin‐like BabA and SabA adhesins of <b><i>Helicobacter pylori</i></b> by fluorescence‐based 2‐D bacterial overlay

Abstract excerpt

Because gastric infection by Helicobacter pylori takes place via the oral route, possible interactions of this bacterium with human salivary proteins could occur. By using modified 1- and 2-D bacterial overlay, binding of H. pylori adhesins BabA and SabA to the whole range of salivary proteins was explored. Bound salivary receptor molecules were identified by MALDI-MS and by comparison to previously established...

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